植物发育与环境适应的分子遗传调控团队
一、团队简介
必赢76net线路“植物发育与环境适应的分子遗传调控”团队。研究方向为植物（作物）重要性状基因遗传调控机制解析及育种应用。团队先后承担20余项科研项目，发表SCI学术论文100余篇。申请发明专利20余项。
二、团队负责人简介
王凯，教授，博士生导师。教育部新世纪优秀人才、江苏省“333高层次人才培养工程”二层次人选；先后获 “闽江学者”特聘教授、“金山学者”特聘教授，福建省引进高层次人才等称号；曾任国家甘蔗工程技术研究中副主任、副院长等职务；曾获中华农业科技奖优秀创新团队奖（等同一等奖）、严家显最高奖教金、江苏省优秀百篇博士学位论文、江苏省遗传学会优秀论文评选特等奖等。主持各类科研项目20项，其中主持国家自然科学基金 6 项、教育部新世纪人才支持计划、国家重点研发计划项目，省自然科学基金等项目多项；指导研究生多人获得省级优秀毕业生和优秀学位论文。现已在Science, Nature Genetics, Genome Res、Plant Cell、PNAS等期刊发表论文100余篇，参编英文著作1部，授权发明专利十余项。现任SCI杂志Functional & Integrative Genomics，Chromosome Res编委，美国自然科学基金评委；担任中国草学会牧草育种专业委员会理事、中国生物工程学会生物农业分会常务理事、国际棉花基因组创新研讨会会员及中国热带作物学会理事等。
团队主持课题：
1.2022 国家自然科学基金青年基金项目、江苏省科技计划项目、江苏省卓越博后计划；
2.2021 国家自然科学基金面上项目；
3.2019 国家重点研发计划子课题；
4.2018 国家自然科学基金面上项目
5.2017 国家自然科学基金海外学者合作研究基金
6.2015 国家自然科学基金面上项目
7.2011 国家自然科学基金面上项目
8.2011 教育部新世纪优秀人才支持计划项目
9.2008 国家自然科学基金青年科学基金
10.2008 江苏省自然科学基金
11.2014 闽江学者特聘教授
12.另外，主持云南省博士工作站及其他合作研究课题十余项。
三、团队其他成员
韩金磊，博士、副教授，硕士生导师。毕业于福建农林大学，从事植物表观遗传，基因表达调控等研究。参与完成多项科研项目。以第一作者在国际知名期刊Plant Cell 以及The Plant Journal发表学术论文。主持国家自然科学基金及江苏省科技计划项目。
陈琪，博士，毕业于东北林业大学，主要从事植物次生代谢调控及植物逆境生理生态学方面的研究。主持江苏省高等学校自然科学研究面上项目1项，主持完成南通市科技项目1项，参与国家级项目多项；以第一作者或通讯作者在BMC Plant Biology、Frontiers in Plant Science、Ecotoxicology and Environmental Safety等期刊发表SCI论文12篇。主要承担植物生物学、植物资源学、中学生物学课程标准与教材分析等生物师范专业主干课程。
寇小兵，博士，副教授、硕士生导师。南京农业大学博士（2018）、博士后（2021）。主要从事植物抗逆境胁迫以及生殖发育的分子机制研究。在《Horticulture Research》、《Journal of Agricultural and Food Chemistry》等国际期刊发表SCI文章多篇。主持国家自然科学基金青年基金一项，参与多项国家自然科学基金面上项目。
Teame Gereziher Mehari，博士后，毕业于中国农业科学院棉花研究所，主要从事棉花等作物的遗传育种研究。
四、团队主要研究方向
1）植物（作物）重要性状决定基因的挖掘与分子遗传调控机制解析；
2）植物基因组结构与演化。
五、发表论著
2025年
1.Han, Jinlei, Guanjing Hu, Yan Dai, Xin Zhang, Jingjing Tian, Jialiang Zhou, Xinqi Xu, Qi Chen, Xiaobing Kou, Lei Xu, Xinyu Wu, Ziying Sun, Jiahui Geng, Lin Li, Chenyu Qiu, Teame Gereziher Mehar, Baohua Wang, Hui Zhang, Xinlian Shen, Zhenzhen Xu, Jonathan F Wendel, and Kai Wang. 2025. 'Centromere-size reduction and chromatin state dynamics following intergenomic hybridization in cotton', PLoS Genetics. Accepted
2.Hu, Guanjing, Zhenyu Wang, Zunzhe Tian, Kai Wang, Gaoxiang Ji, Xingxing Wang, Xianliang Zhang, Zhaoen Yang, Xuan Liu, Ruoyu Niu, De Zhu, Yuzhi Zhang, Lian Duan, Xueyuan Ma, Xianpeng Xiong, Jiali Kong, Xianjia Zhao, Ya Zhang, Junjie Zhao, Shoupu He, Corrinne E. Grover, Junji Su, Keyun Feng, Guangrun Yu, Jinlei Han, Xinshan Zang, Zhiqiang Wu, Weihua Pan, Jonathan F. Wendel, and Xiongfeng Ma. 2025. 'A telomere-to-telomere genome assembly of cotton provides insights into centromere evolution and short-season adaptation', Nature Genetics, 57: 1031-43.
3.Hu, Yan, Jinlei Han, Shangkun Jin, Zegang Han, Zhanfeng Si, Sunyi Yan, Lisha Xuan, Guangrun Yu, Xueying Guan, Lei Fang, Kai Wang, and Tianzhen Zhang. 2025. 'Post-polyploidization centromere evolution in cotton', Nature Genetics, 57: 1021-30.
4.Han, Jinlei, Yan Dai, Jialiang Zhou, Jingjing Tian, Qi Chen, Xiaobing Kou, Ghulam Raza, Baohong Zhang, and Kai Wang. 2025. 'Tissue-specific chromatin accessibility and transcriptional regulation in maize cold stress response', Genomics, 117: 110981.
5.Dai, Yan, Jialiang Zhou, Baohong Zhang, Dewei Zheng, Kai Wang, and Jinlei Han. 2025. 'Time-course transcriptome analysis reveals gene co-expression networks and transposable element responses to cold stress in cotton', BMC Genomics, 26.
6.Zhang, Xin, Yan Dai, Qi Chen, Xiaobing Kou, Eid M. Mehareb, Ghulam Raza, Wei Wang, Ruqin Zhou, Robert Hasterok, Jinlei Han, and Kai Wang. 2025. 'Genome-wide identification of cis-regulatory elements and transcription factors associated with promoted callus formation in Brachypodium distachyon', Plant Cell, Tissue and Organ Culture (PCTOC), 160: 28.
2024年
1.Hu Y, Han J, Jin S, Han Z, Si Z, Yan S, Xuan L, Yu G, Guan X, Fang L, Wang K, Zhang T. Post-polyploidization centromere evolution in cotton. Nature Genetics. (2024). (Accept).
2.Han J, Dai Y, Zhou J, Tian J, Chen Q, Kou X, Raza G, Zhang B, Wang K. Tissue-specific chromatin accessibility and transcriptional regulation in maize cold stress response. Genomics. 117(1) (2024) 110981.
3.Zhang X, Dai Y, Chen Q, Kou X, Mehareb ME, Raza G, Hasterok R, Han J, Wang K. Genome-wide identification of cis-regulatory elements and transcription factors associated with promoted callus formation in Brachypodium distachyon. Plant Cell, Tissue and Organ Culture. (2024).
4.Kou X, Cao P, Zhao Z, Zhang X, Dai Y, Wang K, Wu J, Zhang S. Comparative genomic analysis of the RabGAP gene family in seven Rosaceae species, and functional identification of PbrRabGAP10 in controlling pollen tube growth by mediating cellulose deposition in pear. Int J Biol Macromol. 256(Pt 2) (2024) 128498.
5.Yu G, Zhang B, Chen Q, Huang Z, Zhang B, Wang K, Han J. Dynamic DNA methylation modifications in the cold stress response of cassava. Genomics. 116(4) (2024) 110871.
6.Yu G, Sun B, Zhu Z, Mehareb EM, Teng A, Han J, Zhang H, Liu J, Liu X, Raza G, Zhang B, Zhang Y, Wang K. Genome-wide DNase I-hypersensitive site assay reveals distinct genomic distributions and functional features of open chromatin in autopolyploid sugarcane. Plant J. 117(2) (2024) 573-589.
7.Wang B, Ji M, Fang H, Gu H, Mehari TG, Han J, Feng W, Huo X, Zhang J, Chen Y, Zhang J, Ditta A, Khan MKR, Paterson AH, Chee PW, Wang K. An analysis of lncRNAs related to fiber quality and the discovery of their target genes in a Gossypium hirsutum line with Gossypium mustelinum introgression. Theor Appl Genet. 137(2) (2024) 40.
2023年
1.X. Zhang, Z. Meng, J. Han, H. Khurshid, A. Esh, R. Hasterok, K. Wang, Characterization of meiotic chromosome behavior in the autopolyploid Saccharum spontaneum reveals preferential chromosome pairing without distinct DNA sequence variation, The Crop Journal (2023).
2.W. Ding, Y. Zhu, J. Han, H. Zhang, Z. Xu, H. Khurshid, F. Liu, R. Hasterok, X. Shen, K. Wang, Characterization of centromeric DNA of Gossypium anomalum reveals sequence-independent enrichment dynamics of centromeric repeats, Chromosome Res. 31(2) (2023) 12.
3.K. Wang, H. Zhang, H. Khurshid, A. Esh, C. Wu, Q. Wang, N. Piperidis, Past and recent advances in sugarcane cytogenetics, The Crop Journal 11(1) (2023) 1-8.
4.K. Sun, T.G. Mehari, H. Fang, J. Han, X. Huo, J. Zhang, Y. Chen, D. Wang, Z. Zhuang, A. Ditta, M.K.R. Khan, J. Zhang, K. Wang, B. Wang, Transcriptome, proteome and functional characterization reveals salt stress tolerance mechanisms in upland cotton (Gossypium hirsutum L.), Front. Plant Sci. 14 (2023).
---2022
1.J. Han, D. Lopez-Arredondo, G. Yu, Y. Wang, B. Wang, S.B. Wall, X. Zhang, H. Fang, A.C. Barragan-Rosillo, X. Pan, Y. Jiang, J. Chen, H. Zhang, B.L. Zhou, L. Herrera-Estrella, B. Zhang, K. Wang, Genome-wide chromatin accessibility analysis unveils open chromatin convergent evolution during polyploidization in cotton, Proc. Natl. Acad. Sci. U. S. A. 119(44) (2022) e2209743119.
2.Wang K, Zhang H, Khurshid H, Esh A, Wu C, Wang Q, Piperidis N (2022) Past and recent advances in sugarcane cytogenetics. The Crop Journal，Doi：10.1016/j.cj.2022.08.004
3.Xu Z, Chen J, Meng S, Xu P, Zhai C, Huang F, Guo Q, Zhao L, Quan Y, Shangguan Y, Meng Z, Wen T, Zhang Y, Zhang X, Zhao J, Xu J, Liu J, Gao J, Ni W, Chen X, Ji W, Wang N, Lu X, Wang S, Wang K, Zhang T, Shen X (2022) Genome sequence of Gossypium anomalum facilitates interspecific introgression breeding. Plant Communications:100350
4.R. Hasterok, P. Catalan, S.P. Hazen, A.C. Roulin, J.P. Vogel, K. Wang, L.A.J. Mur, Brachypodium: 20 years as a grass biology model system; the way forward?, Trends Plant Sci. 27(10) (2022) 1002-1016.
5.Huang Y, Ding W, Zhang M, Han J, Jing Y, Yao W, Hasterok R, Wang Z, Wang K (2021) The formation and evolution of centromeric satellite repeats in Saccharum species. Plant J106:616-629
6.Wang Q, Yu G, Chen Z, Han J, Hu Y, Wang K (2021) Optimization of protoplast isolation, transformation and its application in sugarcane (Saccharum spontaneum L). The Crop Journal , 9:133-142
7.Han J, Wang P, Wang Q, Lin Q, Chen Z, Yu G, Miao C, Dao Y, Wu R, Schnable JC, Tang H, Wang K (2020) Genome-wide characterization of DNase I-hypersensitive sites and cold response regulatory landscapes in grasses. Plant Cell 32:2457-2473
8.Lin Q, Wang S, Dao Y, Wang J, Wang K (2020) The Arabidopsis thaliana trehalose-6-phosphate phosphatase gene AtTPPI enhances drought tolerance by regulating stomatal apertures. J Exp Bot, DOI 10.1093/jxb/eraa173
9.Meng Z, Han J, Lin Y, Zhao Y, Lin Q, Ma X, Wang J, Zhang M, Zhang L, Yang Q, Wang K (2020) Characterization of a Saccharum spontaneum with a basic chromosome number of x = 10 provides new insights on genome evolution in genus Saccharum. Theor Appl Genet 133:187-199
10.Huang Y, Chen H, Han J, Zhang Y, Ma S, Yu G, Wang Z, Wang K (2020) Species-specific abundant retrotransposons elucidate the genomic composition of modern sugarcane cultivars. Chromosoma 129:45-55
11.Zhang L, Chen F, Zhang X, Li Z, Zhao Y, Lohaus R, Chang X, Dong W, Ho SYW, Liu X, Song A, Chen J, Guo W, Wang Z, Zhuang Y, Wang H, Chen X, Hu J, Liu Y, Qin Y, Wang K, Dong S, Liu Y, Zhang S, Yu X, Wu Q, Wang L, Yan X, Jiao Y, Kong H, Zhou X, Yu C, Chen Y, Li F, Wang J, Chen W, Chen X, Jia Q, Zhang C, Jiang Y, Zhang W, Liu G, Fu J, Chen F, Ma H, Van de Peer Y, Tang H (2020) The water lily genome and the early evolution of flowering plants. Nature 577:79-84
12.Wang S, Jin W, Wang K (2019) Centromere histone H3- and phospholipase-mediated haploid induction in plants. Plant Methods 15:42
13.Lin Q, Yang J, Wang Q, Zhu H, Chen Z, Dao Y, Wang K (2019) Overexpression of the trehalose-6-phosphate phosphatase family gene AtTPPF improves the drought tolerance of Arabidopsis thaliana. BMC Plant Biol 19:381
14.Hu Y, Chen J, Fang L, Zhang Z, Ma W, Niu Y, Ju L, Deng J, Zhao T, Lian J, Baruch K, Fang D, Liu X, Ruan YL, Rahman MU, Han J, Wang K, Wang Q, Wu H, Mei G, Zang Y, Han Z, Xu C, Shen W, Yang D, Si Z, Dai F, Zou L, Huang F, Bai Y, Zhang Y, Brodt A, Ben-Hamo H, Zhu X, Zhou B, Guan X, Zhu S, Chen X, Zhang T (2019) Gossypium barbadense and Gossypium hirsutum genomes provide insights into the origin and evolution of allotetraploid cotton. Nat Genet 51:739-748
15.Zhang J, Zhang X, Tang H, Zhang Q, Hua X, Ma X, Zhu F, Jones T, Zhu X, Bowers J, Wai CM, Zheng C, Shi Y, Chen S, Xu X, Yue J, Nelson DR, Huang L, Li Z, Xu H, Zhou D, Wang Y, Hu W, Lin J, Deng Y, Pandey N, Mancini M, Zerpa D, Nguyen JK, Wang L, Yu L, Xin Y, Ge L, Arro J, Han JO, Chakrabarty S, Pushko M, Zhang W, Ma Y, Ma P, Lv M, Chen F, Zheng G, Xu J, Yang Z, Deng F, Chen X, Liao Z, Zhang X, Lin Z, Lin H, Yan H, Kuang Z, Zhong W, Liang P, Wang G, Yuan Y, Shi J, Hou J, Lin J, Jin J, Cao P, Shen Q, Jiang Q, Zhou P, Ma Y, Zhang X, Xu R, Liu J, Zhou Y, Jia H, Ma Q, Qi R, Zhang Z, Fang J, Fang H, Song J, Wang M, Dong G, Wang G, Chen Z, Ma T, Liu H, Dhungana SR, Huss SE, Yang X, Sharma A, Trujillo JH, Martinez MC, Hudson M, Riascos JJ, Schuler M, Chen LQ, Braun DM, Li L, Yu Q, Wang J, Wang K, Schatz MC, Heckerman D, Van Sluys MA, Souza GM, Moore PH, Sankoff D, VanBuren R, Paterson AH, Nagai C, Ming R (2018) Allele-defined genome of the autopolyploid sugarcane Saccharum spontaneum L. Nat Genet 50:1565-1573
16.Liu S, Xue C, Fang Y, Chen G, Peng X, Zhou Y, Chen C, Liu G, Gu M, Wang K, Zhang W, Wu Y, Gong Z (2018) Global Involvement of Lysine Crotonylation in Protein Modification and Transcription Regulation in Rice. Mol Cell Proteomics 17:1922-1936
17.Li Y, Zuo S, Zhang Z, Li Z, Han J, Chu Z, Hasterok R, Wang K (2018) Centromeric DNA characterization in the model grass Brachypodium distachyon provides insights on the evolution of the genus. Plant J 93:1088-1101
18.Han J, Masonbrink RE, Shan W, Song F, Zhang J, Yu W, Wang K, Wu Y, Tang H, Wendel JF, Wang K (2016) Rapid proliferation and nucleolar organizer targeting centromeric retrotransposons in cotton. Plant J 88:992-1005
19.Wang K, Yu W (2016) Chromosome Preparation in Rice (Oryza sativa). In: Gary Stacey, Birchler J, Ecker J, Martin C, Stitt M, Zhou J-M (eds) Current Protocols in Plant Biology. John Wiley & Sons, Inc., Hoboken, New Jersey, USA, pp 67-77
20.Shan W, Jiang Y, Han J, Wang K (2016) Comprehensive cytological characterization of the Gossypium hirsutum genome based on the development of a set of chromosome cytological markers. Crop Journal 4:256-265
21.Han J, Zhou B, Shan W, Yu L, Wu W, Wang K (2015) A and D genomes spatial separation at somatic metaphase in tetraploid cotton: evidence for genomic disposition in a polyploid plant. Plant J 84:1167-1177
22.Wang K, Wu Y, Zhang W, Dawe RK, Jiang J (2014) Maize centromeres expand and adopt a uniform size in the genetic background of oat. Genome Res 24:107-116
23.Wang K, Guo W, Yang Z, Hu Y, Zhang W, Zhou B, Stelly D, Chen Z, Zhang T (2010) Structure and size variations between 12A and 12D homoeologous chromosomes based on high-resolution cytogenetic map in allotetraploid cotton. Chromosoma 119:255-266
24.Wang K, Guan B, Guo W, Zhou B, Hu Y, Zhu Y, Zhang T (2008) Completely distinguishing individual A-genome chromosomes and their karyotyping analysis by multiple bacterial artificial chromosome-fluorescence in situ hybridization. Genetics 178:1117-1122
25.Wang K, Guo W, Zhang T (2007) Detection and mapping of homologous and homoeologous segments in homoeologous groups of allotetraploid cotton by BAC-FISH. BMC Genomics 8:178
26.Wang K, Guo W, Zhang T (2007) Development of one set of chromosome-specific microsatellite-containing BACs and their physical mapping in Gossypium hirsutum L. Theor Appl Genet 115:675-682
27.Wang K, Song X, Han Z, Guo W, Yu JZ, Sun J, Pan J, Kohel RJ, Zhang T (2006) Complete assignment of the chromosomes of Gossypium hirsutum L. by translocation and fluorescence in situ hybridization mapping. Theor Appl Genet 113:73-80
28.Song X, Wang K, Guo W, Zhang J, Zhang T (2005) A comparison of genetic maps constructed from haploid and BC1 mapping populations from the same crossing between Gossypium hirsutum L. and Gossypium barbadense L. Genome 48:378-390
六、招聘启事
因研究工作需要，本团队诚招作物遗传育种、遗传学、生物信息学等相关专业博士后或博士毕业生。
应聘资格：
1．热爱科研，工作积极主动，态度严谨，责任心强，具备良好的团队合作精神。
2．具备独立开展科研的能力；以第一作者身份发表过SCI论文。
相关待遇：详见76net必赢人事处网站https://rsc.ntu.edu.cn/xgdy/list.htm
有意者请将个人简历、导师推荐信发电子邮箱：kaiwang92@sina.com
联系人：王老师、韩老师